Uric acid enhances the antitumor immunity of dendritic cell-based vaccine
نویسندگان
چکیده
منابع مشابه
Uric acid enhances the antitumor immunity of dendritic cell-based vaccine.
Uric acid (UA) released from dying cells has been recognized by the immune system as a danger signal. In response to UA, dendritic cells (DC) in the immune system mature and enhance the T cell response to foreign antigens. It is conceivable that the antitumor immunity of a tumor vaccine could be promoted by the administration of UA. To test this concept, we applied UA as an adjuvant to a DC-bas...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep16427